Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

The magazine put his net worth at $3.5 billion, down $1 billion from the rankings it issued a year ago.
James Kynge
埃米?珀勒(Amy Poehler)狂吻博诺(Bono),蒂娜?费(Tina Fey)吐槽乔治?克鲁尼(George Clooney)只爱年轻女人,而诡异的是马特?戴蒙(Matt Damon)当晚数次“中枪”。
Participants in the study were between the ages of 18 and 44 and were asked to run twice – with and without shoes. After completing their quick runs, researchers found that the heart rate and overall run speed of each participant had no effect on memory, but the presence of shoes or bare feet did. The researchers have hypothesized that the need to engage the mind while running barefoot to avoid pebbles or other impediments could have a positive impact on a person's ability to remember things. If you're an adventurous person, you might try taking a barefoot jog around the block before your next test or before you need to remember something important.
只跟那些能凸显你聪明的人做朋友,哪怕他们觉得你坏坏哒。
[pr?'tekn]
单词enterprise 联想记忆:
……被要求向面试官简单介绍自己,结果她没有什么可说的。
['p?:ts]
世界卫生组织宣布寨卡构成国际关注的公共卫生紧急事件
So, before the world gets the better of you and slaps a title on your forehead, create a unique manifesto of what you think you are.
Seychelles
For the full year, profits rose 3.3 per cent, the slowest growth since at least 2008, when Chinese manufacturers were slammed by the global financial crisis.
Were you late to work yesterday because you couldn't remember where you put your car keys? Did you completely forget about a coffee date last week with a friend and only remember when you got a text asking, "where are you?" Can you no longer remember the name of your favorite elementary school teacher? Memory problems impact just about everyone to a certain degree, but science suggests you might be able to improve your memory, as well as reduce the likelihood of Alzheimer's and dementia, by engaging in certain activities, eating specific foods, and using certain mnemonic devices.
现代中国经销商Wang Rongzhen7月20日向路透社指出,现代汽车已经缩减提供给中国进口经销商的产品阵容,仅提供一款车型供销售,而在中国国产的车型不断增加。
国内生产总值达到74.4万亿元,增长6.7%;
6年来第一次,新的挑战者领衔英国《金融时报》高管MBA(EMBA)课程排行榜。
密码管理应用设计商Splashdata发布了一份“25个最常见密码” 榜单。
最佳录影带:Little Big Town《Tornado》
As we ring in the New Year, let’s take stock of where we are at with the oil markets. 2014 proved to be a momentous one for the oil markets, having seen prices cut in half in just six months.
非常感谢Aicha Nezzar在脸谱—--世界英语论坛上为我们分享这篇佳作。
Big Little Lies
为大批来自欧洲经济区以外的学生安排签证难度较大,这在一定程度上解释了为何英国商学院在国际课程经验方面表现奇差,有14所英国商学院位于这项指标排名的后半部分。
The Gwen Stefani campaign ran on several apps, including Tango, the Silicon Valley-based messaging app. Tango earns money on ads within a user’s inbox, but it has adopted Swyft’s platform because the ads are in line with the way people already use Tango, says Richard Rabbat, vice president of Advertising and Platform at Tango. A year ago, Tango decided not to sell stickers, because asking users for money creates too much friction, he says. “Putting a payment gate in the way of communication is not the right experience we want to give to our users,” Rabbat says. Ergo, ad campaigns from Swyft.
French business schools top the 2017 ranking. Edhec Business School, based in Lille and Nice, leads the field for the first time. HEC Paris, which dominated this ranking since its first edition in 2011, drops to second place.


1. Peaceful Era
她说,零售业务“起步不久,好坏参半”。她表示,亚太所有国家都有大量工作要做,并补充称,澳大利亚的事例证明,就吸引散户兴趣而言,监管改变可以带来显著不同。
Attractions: Food, culture and scary stories


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

Cnzz.com的报告还讨论了目前在中国网络游戏行业盛行的装备收费模式问题。举例来说,很多美国游戏公司都是按照时间收费的,但大多数中国网络游戏都采取了装备收费模式,玩家可以免费试玩。用户玩游戏的时间越长,就越有可能花钱购买游戏装备,以获得更高的游戏级别。但这也意味着花钱最多的玩家就在游戏中表现最好。
周三,北京市发改委主任卢彦在新闻发布会上说:“我们将会在通州开展297个项目,例如建设地铁线和高速路及改善生态环境。”
我们发展出人工记录声音的技术已经有几十年了,但是人工植入器官在耳朵这一领域没有任何改变。你可能认为生长在头两边的肉块极易替换,因为它们只是皮和软骨,而不是复杂的器官。事实上,科学家在制作假耳上并没有做得非常出色。传统的替代耳朵看起来或感觉起来都像塑料玩具。
Some 695 million netizens used mobile phones to access the Internet in 2016, with a growth rate exceeding 10 percent for the third straight year, the report said. Smartphone-based Internet use accounted for 95.1 percent of all Internet users, up from 90.1 percent in 2015.

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

单词stroke 联想记忆:

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

intelligence
这种成功的感觉本身也可以带来一种身份认同。

Aoki-san is a pleasure to work withon storyboard. With Aoki-san on the team it feels like a sure thing. The visionof these animations will be perfect.
勉强会。民主党将在11月中期选举中重新赢得对众议院的控制权。尽管他们要到2019年1月才能掌控众议院,但他们将马上开始为众议院司法委员会(House Judiciary)启动弹劾做文书方面的准备。特朗普将称此举为“政治迫害”。但在特朗普怪诞的总统任期又持续了一年之后,民主党将几乎不可避免地展开造势活动,誓要让特朗普承担责任。在此之前,无论罗伯特米勒(Robert Mueller)的调查发现了什么,都不可能让足够多的共和党人倒戈反对特朗普。
美国就业市场笼罩着重重阴云──特别是遭遇增税、减支双重打击的可能性,即“财政悬崖”。[qh]
几家与韩国有关系的机构已经感受到了北京方面对萨德计划的怒火。上个月,由于乐天(Lotte)出让土地用于部署萨德平台,中国官方新闻机构新华社(Xinhua)向乐天发出了强硬警告。乐天是韩国最大的企业之一。
一次投入全部很少能够成功。虽然确实有人倾其所有,在六个月或一两年之后成为赢家,但这只是个案。对于任何初创公司来说,风险管理都是一个重要元素,账目平衡至关重要。如果你在最开始承担的风险更少,你就更容易消化损失。而这些损失将是必不可少的、富有价值的教训。
这位工作人员说道:“她注册时说自己姓韩,也不是像媒体上报道的姓苏。”

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


北京大兴瀛海“限竞房”限价5万5


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


Local champions
室内环境:这栋砖砌结构、灰泥粉饰并铺着瓷砖屋顶的两层楼房屋由Dorr & Dorr公司设计,于1916年完工,近15年内曾经翻修。该房屋采用了半牧场、半工匠艺术的设计风格,运用了简洁的线条、开敞式空间、典雅的木制品和彩色玻璃等设计。翻修工程由明尼阿波利斯市Sala建筑公司的约瑟夫·麦茨勒(Joseph Metzler)完成。
萝丝王在中国长大,在那里学会了计算机编程。大学毕业后,她希望到美国工作。第二年,《中国学生保护法案》(Chinese Students Protection Act)获得通过,萝丝王获得了休斯敦大学的计算机科学硕士学位。2001年9月11日之前,她曾在多家硅谷初创公司(包括成立自己的公司iBizWomen.com)工作。911事件让她产生了创办Binary Group的想法。Binary Group是一家与联邦政府合作的科技咨询公司。过去16年间,这家公司帮助客户节省的资金不计其数——比如美军第20支援司令部(Army 20th Support Command)就在五年时间内共节省了6,000万美元卫星通信带宽开支。
Transforming and upgrading the real economy through innovation
同时,大批与比特币相关的创业公司于2014年创建,表明比特币势头强劲。我们没有比特币新创企业的详尽名单,但几乎可以肯定的是,2014年成立的比特币新创企业的数量,高于此前任何年份。融资平台AngelList发给《财富》的数据证实了这一点。2011年,5家比特币初创公司在AngelList上登记。2012年,这个数字增加到13家;2013年跃升至193家;2014年更是暴增至566家。【但并非所有创业公司都会(立即)在AngelList上登记。】此外,正如巴里o希尔伯特在推特上所言,1月8日,比特币日交易总量创下历史新高。
Common industries for college startups include catering, agriculture, IT, transportation, education and culture. 13.8% of the entrepreneurs were interested in hospitality and catering, while 13.7% chose agriculture, the report said.
We will explore new forms of social governance.
故事背景设定于《星球大战3:西斯的复仇》和《星球大战4:新希望》之间,起义军盗取死星设计图,将很有可能成为被重金追杀的对象。对于电影详细情节,我们也不是很清楚。
现在似乎可以放心地预言,2017年余下时间会出现更多噪音、甚少进展,而这将继续对贸易和英国经济造成破坏。
The movie takes place a year after the events of Finding Nemo and follows the journey of Dory to find her parents. Dory is helped by Nemo and Marlin in this epic adventure along the coast of California. You will also see some new characters introduced in the film.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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The Bloomberg soft commodities index has gained 21 per cent, compared with 24 per cent for industrial metals and 1.5 per cent for energy.
获奖者:加拿大总理贾斯廷·特鲁多
That figure is more than two times the city's population of about 10 million.
complex

Whiteness, in this context, is more than just skin color. You could define it as membership in the “ethno-national majority,” but that’s a mouthful. What it really means is the privilege of not being defined as “other.”

  • Only the first three authors are listed, followed by "et al."
  • 上海中介小伙为卖房 已和客户结4次婚
  • 红星美凯龙捐赠千万家居为困境儿童建一个“家”


人们对于可穿戴设备销量的估计各不相同。研究公司IDC认为,这类设备今年的销量将超过1,900万件量,达到去年的三倍以上。到2018年,它的销量将会达到1.119亿件。瑞士信贷(Credit Suisse)预计,在接下来的2-4年中,这个行业的价值将会高达300亿至500亿美元。不过,在这一切实现之前,这个方兴未艾的市场需要摆脱人们对于“穿戴这种设备就是出丑”的成见。
vt. 作 ... 姿

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